Nanoemulsion: An advanced vehicle for anti-cancer drug delivery
Usama Ahmad1, Juber Akhtar1, Farhan Jalees Ahmad2
1. Department of Pharmaceutics, Integral University, Kursi Road, Lucknow, India
2. Department of Pharmaceutics, Jamia Hamdard, New Delhi, India
Nanomedicine has the potential to significantly change the course of diagnostics and treatment of life-threatening diseases, especially cancer. Cancer nanomedicine has been increasingly worked upon and widely investigated in nanopharmaceutical research. In recent years, the successful introduction of several novel nanomedicine products into clinical trials and even onto the commercial market has shown successful outcomes of fundamental research into clinics. One such novel design is the introduction of modified nanoemulsion for drug delivery. Nanoemulsions comprise a specified class of multiphase colloidal dispersions. They are transparent and their sizes lie in the nanometric range. Nanoemulsions are usually biphasic system, consisting of either oil dispersed in water or vice versa and stabilized by a surfactant. Various features of nanoemulsions, including ease of manufacture, stability and high loading capacity, make them particularly well-suited to targeted drug delivery of anti-cancer therapeutics. Improved nanoemulsions are achieved by internal, external, surface and interface modifications of the formulation which are adapted for targeting cancer cells and sparing healthy cells.