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83 papers. Watch letures, learn, Participate in panel discussions
There are three days of 75+ researchers presenting papers LIVE!
Watch or if you like, participate in live discussions via internet at your office or home with headset or microphone. You can learn, listen and watch presentations live or for seven days after the conference.
these are two people presenting nano papers
3D Visualization of Unlabeled Transplanted Stem Cell in Infarcted Rat Heart by High-Resolution X-ray Microtomography.
Alessandra Giuliani, Università Politecnica delle Marche, Dip.SAIFET, Via Brecce Bianche, Ancona, Italy.
Summary: X-Ray microtomography (microCT) has been successfully used in order to provide information about bone, lung, kidney and biomaterial structure. However, some concerns persist in the
scientific community for its in-vivo and ex-vivo applicability in longitudinal imaging of cell fate. Specifically, the possibility to study remote time points after cell injection seems to be limited
by the lack of information on important variables such as cell proliferation and cell death. This appears to be due to the need of cell labeling using iron oxide nanoparticles that may accumulate in
macrophages after death of delivered cells, and hence their signals do not precisely reflect stem cell fate (Terrovitis et al, Circulation 2008; Higuchi et al, J Nucl Med 2009). The present study shows that X-ray computed microCT in ex-vivo conditions may offer the unique possibility to detect, in the infarcted rat heart one week after injection, the 3D spatial distribution of Stem Cells, without the use of any contrast agent. Contrast between myocardium and injected stem cells relies on the presence of phase
contrast and not on iron oxide nanoparticles as employed in several microCT studies performed in absorption conditions. The obtained 3D images represent a very innovative result because they definitively avoid the possibility that bright spots in 3D microCT images represent macrophages that have phagocytized iron nanoparticles, or particles that have been expelled from injected cells into the
interstitium. This work provides evidence that the Authors’ conclusions (Giuliani et al., Journal of Tissue Engineering and Regenerative Medicine, in print) on cell migration away from the infarcted area are not speculative. Finally, observations made by the present investigation strongly support the contention that
phase-contrast microCT represents a new 3D-imaging way to investigate the cellular events involved in cardiac regeneration and represents a promising tool for other applications in regenerative medicine.
Alessandra Giuliani, Assistant Professor, Università Politecnica delle Marche, Dip.SAIFET, Via Brecce Bianche, Ancona, Italy; Consorzio Nazionale Interuniversitario per le Scienze fisiche della Materia, Ancona Unit, Ancona, Italy; Istituto Nazionale Biostrutture e Biosistemi, Roma, Italy. Alessandra Giuliani, PhD, received her Degree in 1998 and in January 2003 completed the PhD Course in "Materials, Water and Soil Engineering". From March 2006 she serves as Assistant Professor in Physics at the Polytechnic University of Marche. The scientific activity of Dr. Giuliani is devoted to the study of issues related to tissue engineering and regenerative Medicine through non-destructive advanced techniques as X-Ray computed microtomography and X-Ray Micro-diffraction.
Moreover, her activity is also devoted to the study of cultural heritage items and technological materials by advanced experimental methods.
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Synergistic Development of Targeted Nanobeacons and Novel Imaging Modalities for Early Detection of Vascular Disease.
Dipanjan Pan, Medicine at the Division of Cardiology, Washington
University in St. Louis, USA.
Summary: The unprecedented potential of nanoparticles for early detection, diagnosis and therapy of a disease has emerged as an interdisciplinary area, which shows promises to understand the
components, processes, and dynamics of a disease at a molecular level. This talk will highlight our results with "soft" (flexible) theranostic metal nanobeacons developed as environmentally responsive, biologically-optimized nanometer-sized particles for optical and x-ray based imaging modalities. A new class of molecular imaging agent has been developed based on bismuth to detect and quantify intraluminal fibrin presented by ruptured plaque in the context of computed tomography angiograms without calcium interference (spectral CT). The importance of photo acoustic tomography (PAT) to differentiate early vulnerable neoangiogenesis from mature vessels with gold nanobeacons will also
be discussed.
Dipanjan Pan, Assistant Professor of Medicine at the Division of Cardiology, Washington University in St. Louis, USA. Dr. Pan has over 50 original publications, numerous abstracts, and patents in
the area of materials science, chemistry and nanomedicine. Dr. Pan joined the WU faculty in 2007. Subsequently, he co-invented several nanoparticle platforms for molecular imaging application with CT,
MRI, optical and photoacoustic imaging. His research is broadly aimed at the understanding and developing novel lipid-based and polymeric nanoparticle platforms for molecular imaging, drug
delivery and non viral gene delivery applications related to cardiovascular and cancer diseases. He presently serves as the editorial board member of the Journal of Biotechnology and Biomaterials and World Journal of Radiology.
=========conference info==============
TMs 1st world cardiovascular, diabetes, and obesity ONLINE
conference -
September 22-24, 2011.
Worldwide participate live!
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Doctors, Researchers, Patients - Anyone interested
There are three days of 75+ researchers presenting papers LIVE! Watch or if you like, participate in live discussions via internet at your office or home with headset or microphone. You can learn, listen and watch presentations live or for seven days after the conference.
Major symposiums of interest include, but not limited to
* Cardiology disease * Atherosclerosis
* Hypertension * Angiogenesis
* Vascular diseases * Diabetes
* Obesity * Preventive medicine
You will receive many benefits
* Follow major research developments in a variety of hot areas;
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AGENDA - schedule of 83 speakers and panel discussions
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Conference is September 22-24 view presentations online
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