Full member
The Mass Spectometry Specialist will manage research projects and function independently in both administrative and research capacities. The person will regularly work in collaboration with individuals in the lab and support daily laboratory operation, the writing of grant proposals, and in writing human protocols. This person will also analyze and interpret results, summarize, and report data to the principal investigator and other collaborators as well as present findings in laboratory meetings with a view toward further refinement of research goals from input from colleagues. The individual will develop, transfer, perform, and validate assays for various types of mass spec analysis and use these techniques in support of other projects and goals within the laboratory. This person will present findings to the scientific community through publications in relevant journals and through presentation of results at conferences, seminars, and scientific meetings. This individual will also help with managing and reporting routine operational activities such as ordering supplies and materials, reviewing inventory, maintaining up to date records of tests and general preventative maintenance of equipment. This individual should be an enthusiastic, people-oriented LC/MS Metabolomics and Proteomics Applications Professional who will work directly with world-class scientists at Johns Hopkins University School of Medicine, School of Public Health and researchers at premier institutions in the Baltimore, Maryland region.

This position is located in Baltimore, Maryland with occasional travel to Wilmington, Delaware.

In this role, you will enable advances in research by providing technical expertise and training to clinical scientists and principle investigators who are using Agilent's high-end LC-MS instrumentation (QQQ and QTOF), and other vendors instrumentation. You will work directly with these scientists to design and conduct experiments, develop new workflows that allow for seamless execution from sample preparation to results, analyze and interpret data, and troubleshoot as needed. The individual will train directly with industry Applications Scientists.

DUTIES AND RESPONSIBILITIES:
  • Work directly with the Executive Directors of the CRIB in strategic planning, method development and execution, marketing and meeting customer needs
  • Provide technical and applications assistance in response to customer inquiries for QQQ and QTOF applications
  • Conducting in-house demonstrations and training on Chip Cube LC, QQQ and QTOF directly with clients
  • Contributing to the development of new clinical applications
  • Maintain web page and assist in maintaining customer accounts with administrative support
  • Communicate with clients and collaborators on details in regards to projects individualized requirements of each project
  • Method development and validation for QQQ and QTOF applications
  • Participation at national meetings to present findings, demonstrate services, and explore future collaborations
  • Manages independent research projects in full collaboration with the Principal Investigator, post doctorial fellows, and other laboratory staff. Aids in identifying and selecting best options for scientific strategies and experimental design based on literature review, technical training, and collaboration with colleagues.
  • Analyzes and interprets results within the context of larger research/grant goals. Summarizes and reports data to Principal Investigator and other collaborators. Presents findings in laboratory meetings with a view toward further refinement of research goals from input from other colleagues.
  • Develops, transfers, and performs assays using micro flow and nano flow UPLC and mass spectrometry between and across multiple platforms including, but not limited to orbitrap, time of flight, and triple quad tandem mass spectrometry platforms. Uses these techniques in support of targeted proteomics projects as well as in collaboration with other projects and goals.
  • Validation of all assays including precision, linearity, carryover, limit of detection, limit of quantitation, matrix effect, patient correlation. Create and implement laboratory standard operating procedures of all aspects of sample handling and analysis.
  • Manage up to two B.Sc. level individuals
  • Communicate with clients and collaborators on details in regards to projects individualized requirements of each project
  • Method development and validation for QQQ and QTOF applications
  • Participation at national meetings to present findings, demonstrate services, and explore future collaborations
  • Works in collaboration with people in the lab and supporting daily laboratory operation, grant proposals/human and animal protocols. Maintains regular interaction with students, vendors, post-doctoral fellows, faculty members, and clinical fellows.
  • Be capable of and comfortable with incorporating new technologies into the laboratory, including but not limited to, coordination of facilities modification to installation, oversight of installation process, attending training for the operation and maintenance of new instrumentation, and training of other lab personnel in the operation and data acquisition associated with the new technology.
  • Presents findings to the scientific community at large through publication of results in relevant journals and through presentation of results at conferences, seminars, and scientific meetings. Working, managing, and reporting routine operational activities such as; ordering supplies and materials, reviewing inventory, maintaining up to date records of tests, and preventative maintenance of equipment.
  • Markets the CRIB through talks, direct laboratory visits and other activities as directed by the CRIB executive
  • Up to 15% of time may be spent in travel executing the above responsibilities.
Qualifications:

Bachelor's degree in biology, chemistry or related field required plus four years experience in a comparable laboratory performing relevant techniques.

Ability to quickly learn and develop new laboratory skills and techniques. Excellent communication skills, exemplary experimental design skills, and tactful assertive interpersonal skills. Strong project management experience and skills within a lab environment are highly desirable.

Hands-on experience in the field of biological mass spectrometry and quantitative mass spectrometry essential. Experience with or understanding clinical and peptide quantitation applications by QQQ/QTOF preferred. Experience with, or understanding of, applications adjacent to QTOF/QQQ helpful.

Proficiency using high level programming languages for data acquisition, analysis and instrumentation control. Exceptional skills in quantitative data analysis.

Application here

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