The Laboratory for Membrane Physiology and Technology (MemPhysTech) in the
Department of Physiology, University of Freiburg i. Br. (Head: Prof. Jan C. Behrends) is
seeking candidates for a PhD fellowship to investigate and develop nanopore-mediated
characterization and discrimination of chemically distinct polymers, using pore-forming
membrane proteins (alpha-hemolysin, aerolysin, MspA) reconstituted in synthetic lipid membrane
arrays1-4. The fellowship is available immediately for a total of 36 months. It is funded by the
Deutsche Forschungsgemeinschaft (DFG) in the framework of the International Research
Training Group (IRTG) on 'Soft Matter Science: Concepts for the Design of Functional
Materials' Freiburg and Strasbourg. The project is being pursued in close collaboration with
the Precison Polymer Synthesis Group at the Institut Sadron of the CNRS at Strasbourg
(Head: Prof. Jean-François Lutz). We are looking for a highly research-committed individual
with a firm background in either (Bio)Physics, (Bio)Chemistry, Structural Biology or
Electrophysiology.
The grant of the fellowship amounts to 75% of the E13 salary bracket of the German Public
Service Wage Agreement (TvÖD). Typical net monthly earnings after tax: 1640 €
-for background on the IRTG see http://www.softmattergraduate.uni-freiburg.de
-for project details see http://www.softmattergraduate.uni-freiburg.de/project/2015-2019/newproject-
c7.pdf
(1) Baaken, G.; Sondermann, M.; Schlemmer, C.; Rühe, J.; Behrends, J. C. Planar Microelectrode-Cavity Array for High-Resolution and Parallel Electrical Recording of Membrane Ionic Currents. Lab Chip 2008, 8, 938-944.
(2) Baaken, G.; Ankri, N.; Schuler, A.-K.; Rühe, J.; Behrends, J. C. Nanopore-Based Single-Molecule Mass Spectrometry on a Lipid Membrane Microarray. ACS Nano 2011, 5, 8080-8088.
(3) del Rio Martinez, J. M.; Zaitseva, E.; Petersen, S.; Baaken, G.; Behrends, J. C. Automated Formation of Lipid Membrane Microarrays for Ionic Single‐Molecule Sensing with Protein Nanopores. Small 2015, 11, 119-125.
(4) Baaken, G.; Halimeh, I.; Bacri, L.; Pelta, J.; Oukhaled, A.; Behrends, J. C. High-Resolution Size-Discrimination of Single Non-Ionic Synthetic Polymers with a Highly Charged Biological Nanopore. ACS Nano 2015, 150531140658005.
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