Title of the paper: 

Developments of Immobilized Surface Modified Piezoelectric Crystal Biosensors for Advanced Applications

Authors:  

Sumit Pramanik, Belinda Pingguan-Murphy and Noor Azuan Abu Osman

University/Institute: 

Department of Biomedical Engineering, Faculty of Engineering, Centre for Applied Biomechanics, University of Malaya, Kuala Lumpur 50603, Malaysia

Abstracts:

The development of biosensors has seen recent growth owing to their wide range of potential 

applications from the defending of bioterrorism to the detection of various diseases. Recent 

investigations in highly sensitive nanomaterials containing nanotechnology suggest the possibility of 

its advanced applications as biosensors in different biomedical fields. Besides highlighting the 

characteristic features of different classes of advanced biosensor across different fields of potential 

application, this article gives a clear overview of some specific investigations related to the surface 

immobilizations of piezoelectric biosensors employing effective materials and advanced technologies. 

Further, the current development of piezoelectric biosensors in the detection of potential biomolecules 

for advanced biomedical applications is critically reviewed. The qualitative and quantitative sensitivity 

of piezoelectric biosensors, various expressions of resonant frequency shift with changes in mass, 

thickness, density, and stress for piezoelectric materials are distinctly explored. The importance of 

several novel nanomaterials for the detection of various diseased biomolecules is clearly illustrated.

This study concludes that proper selection of materials is potential to bring improvement in quality as 

well as reduction in cost of advanced biosensor devices.

Links to the paper (link to the journal webpage): 

http://www.electrochemsci.org/papers/vol8/80608863.pdf

http://www.electrochemsci.org/list13.htm )

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