Research Associate: Single-molecule imaging of receptor triggering on live T-cells (Fixed Term)

Fixed-term: The funds for this post are available for 2 years in the first instance.

Applications are invited for the post of Research Associate within the groups led by Professor David Klenerman and Dr Steven F. Lee, in a collaborative project with Professor Simon Davis at The University of Oxford. The project exploits novel single-molecule fluorescence imaging methods to determine how key signalling proteins in the cell membrane reorganise to initiate signalling at the contact between two cells, initiating the adaptive immune response. 

The main role of the Post-Doctoral Research Associate will be to perform live single molecule imaging and quantitatively analyse the data obtained from these experiments using custom software. This will involve development and optimisation of the fluorescence imaging protocols and modifying and adapting existing analysis software.

Applicants should have a PhD in biophysics, physical chemistry or other relevant discipline and preferentially experience in quantitative imaging or single molecule fluorescence. This project is suitable for a physically trained scientist who is interested in doing multi-disciplinary research since full support is provided on the biological side by Professor Davis's group. 

To apply online for this vacancy, please click on the 'Apply' button at

This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload your Curriculum Vitae (CV), a covering letter and publications list in the Upload section of the online aplication. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application. 

For queries regarding applying online for this post, please contact Sharon Connor (

Please quote reference MA05339 on your application and in any correspondence about this vacancy.

The Department holds an Athena SWAN bronze award for women in Science, Technology, Engineering, Mathematics and Medicine. 

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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