David Lyndel

its new and basically in name-only at this stage. it arose from weekly breakfast meetings between myself and three others. we seem to be in agreement to approach neuroscience via nanovectors for imaging, diagnostics, treatments and therapies. we are thinking along the lines of AD, PD and brain cancers and tumours. the first two are neurodegenerative diseases as you know and the others can be. we see neuronal decay in AD. thinking of concepts of using nanoparticles to remove the plaques and neurofibrillar tangles. one challenge facing neuroscience is the clear early diagnosis of AD. Of course this approach depends on using biomaterials that are biocompatible or as I prefer to say, exhibit biocompatibilty. To me there is a difference. we have only the front page up on our website for we are all busy with other obligations. (we are a work in progress) if we focused more on cancer-only funding would be more readily available. but we are in agreement that since we are increasingly facing a growing aged population it is crucial to address these issues. i myself have early sporadic PD or so it is thought. so maybe i have a vested interest. it effects about 2% of folks over 65 but i have quite a ways to go to reach that hurdle. PD symptoms can only be alleviated. this disease requires that we address the fact there is no cure to stop the neurodegeneration. pathologically its likely that a lack or loss of dopainergic neuromelanine neuron containers. protection of the nigra neorons is crucial. identification and targeting the effected cells in both AD and PD is one of the many challenges. i believe once the nanocarrier enters the neuronal cell it must navigate the cell's enviroment to correct the disease. in PD we need to stop the neuromelanin containg neurons from taking up metals and toxics like catechol. basically the cells poison themselves. I could go on and on but i will spare you. protein identification and other biomarkers could be enhanced by using nano-carriers as with doping, etc. increasing the effectiveness of drugs is critical. triggering and producing better immunotherapies is one approach. currently we are going to go with the concept of information exchange of non-copyrighted materials and methods as well as those we get permission to post on the website. we also hope to serve as a link to links as a node in the exchange of this science information. we also will be making open source ware available as we are able. there is no doubt systems biology is going to play a large role in nanomedicine. also an area that is in its infancy is materials informatics. it saves alot of funds but still has bottlenecks and shortcomings. but i see all this as not a problem but just another challenge. thank you for your kind greetings.

Comments

Judith Light Feather June 13, 2008 at 5:27pm

Hi David,
Thanks for the invitation. Check out our websites for nanoeducation at www.tntg.org and Nanonews at www.NanoNEWS.TV We specialize in finding education solutions by gathering resources that can be used by teachers/students globally without charge.
Our news site is designed to inform the public about nano science growth and commercialization. Let us know if we can be of service to your project in the future.
Respectfully,
Judith
Charlie Chow June 13, 2008 at 2:48pm

Dear David,
We are a Nano-Integrator and bridge the commercial gaps.
My email : charlie@nanogh.com
Best regards,
Charlie Chow
Tunde Kovacs June 13, 2008 at 12:10pm

Hi David,

Thank you for your invitation.
How are you?
Please contact me in email:tundeanna@gmail.com

Have a nice day!
Best regars
Tunde
David Lyndel June 13, 2008 at 4:22am

its new and basically in name-only at this stage. it arose from weekly breakfast meetings between myself and three others. we seem to be in agreement to approach neuroscience via nanovectors for imaging, diagnostics, treatments and therapies. we are thinking along the lines of AD, PD and brain cancers and tumours. the first two are neurodegenerative diseases as you know and the others can be. we see neuronal decay in AD. thinking of concepts of using nanoparticles to remove the plaques and neurofibrillar tangles. one challenge facing neuroscience is the clear early diagnosis of AD. Of course this approach depends on using biomaterials that are biocompatible or as I prefer to say, exhibit biocompatibilty. To me there is a difference. we have only the front page up on our website for we are all busy with other obligations. (we are a work in progress) if we focused more on cancer-only funding would be more readily available. but we are in agreement that since we are increasingly facing a growing aged population it is crucial to address these issues. i myself have early sporadic PD or so it is thought. so maybe i have a vested interest. it effects about 2% of folks over 65 but i have quite a ways to go to reach that hurdle. PD symptoms can only be alleviated. this disease requires that we address the fact there is no cure to stop the neurodegeneration. pathologically its likely that a lack or loss of dopainergic neuromelanine neuron containers. protection of the nigra neorons is crucial. identification and targeting the effected cells in both AD and PD is one of the many challenges. i believe once the nanocarrier enters the neuronal cell it must navigate the cell's enviroment to correct the disease. in PD we need to stop the neuromelanin containg neurons from taking up metals and toxics like catechol. basically the cells poison themselves. I could go on and on but i will spare you. protein identification and other biomarkers could be enhanced by using nano-carriers as with doping, etc. increasing the effectiveness of drugs is critical. triggering and producing better immunotherapies is one approach. currently we are going to go with the concept of information exchange of non-copyrighted materials and methods as well as those we get permission to post on the website. we also hope to serve as a link to links as a node in the exchange of this science information. we also will be making open source ware available as we are able. there is no doubt systems biology is going to play a large role in nanomedicine. also an area that is in its infancy is materials informatics. it saves alot of funds but still has bottlenecks and shortcomings. but i see all this as not a problem but just another challenge. thank you for your kind greetings.
Jose Feneque, DVM June 10, 2008 at 11:36pm

Hello David! Greetings from Georgia. Can you tell us more about your organization "The Nanomedicine Project".

Jose Feneque, DVM
TINC June 10, 2008 at 8:21pm

welcome to the nanoscience network

andras paszternak, editor

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