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  • This is a link to an abstract on scanning ion conductance microscopy recently published in Nature Methods. http://www.nature.com/nmeth/index.html. This is an SPM technique that uses a pipette to scan instead of a silicon probe. If you are interested in high resolution live cell imaging you should take a minute to check it out. The lateral resolution is around 10nm for living cells.
  • Thanks for the welcome. I will post some images and information on this soon.
  • Welcome Brad!!!! I am very interested in the imaging of you! May be you can post an image on this site? As far as I know Andras, the material is a special kind of glass which you can order. If you want to know the exact details, let me know.....
  • Hello, my interest in nanopipettes is related to imaging. I work with a new SPM technique, scanning ion conductance microscopy (SICM). The technique uses a nanopipette to produce high resolution images of live cells.
  • From which material is this nanopipette?
  • Thanks Yuri! The SEM picture I posted above is a sample of a nanopipette created by Alessandro Formenti, also member of this site. Greets, Georgette
  • You may be interested in the method of nanopipette assembly prosed in the following paper:
    J. R. Freedman, D. Mattia, G. Korneva, Y. Gogotsi, G. Friedman, A. K. Fontecchio, Magnetically Assembled Carbon Nanotube Tipped Pipettes, Applied Physics Letters 90, 103108 (2007)
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Are carbon nanopipettes better than glass micropipettes?

We produce carbon-tipped pipette to decrease the diameter and add functionality (SERS, electrochemistry, etc.) to glass micropipettes, which are currently used for cell injections. See:M. G. Schrlau, E. Brailoiu, S. Patel, Y. Gogotsi, N. Dun, H.H. Bau, Utilizing Carbon Nanopipettes to Characterize Calcium Pathways in Cancer Cells, Nanotechnology 19, 325102 (2008)We can make much smaller nanopipettes now, but we are still looking for applications in which carbon nanopipettes with about 100 nm…

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