When exposed to biological fluids such as blood plasma, nanoparticles adsorb proteins and other biomolecules from the fluid. The adsorption is a dynamic process. The composition of the so-called protein corona depends on the respective concentrations of the proteins in the fluid and on their affinities to the nanoparticles. Understanding the structural and dynamic properties of the corona at the molecular level is necessary to use nanoparticles safely in industry or nanomedicine.

Im Rahmen des Schwerpunktprogramms SPP1313 “Biological Responses to Nanoscale Particles“ suchen wir eine Doktorandin/einen Doktoranden (aus den Bereichen Physik, Biophysik, Chemie, Biochemie), um die Wechselwirkungen zwischen Nanopartikeln, Proteinen und Zellen mit fluoreszenzbasierten (FRET, FCS, live-cell imaging, high-resolution microscopy etc.) und spektroskopischen Methoden (UV/VIs, CD, IR) zu untersuchen.
Wir sind eine interdisziplinäre Arbeitsgruppe, in der Physiker, Chemiker und Biologen zusammenarbeiten.


Anfangsdatum: 21. Juli 2011

geschätzte Dauer: 3 Jahre

 

Contact: karin.nienhaus(a)kit.edu

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  • hope to participate in this study,please give me the requirement in addition to the Ph.D degree
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