Gender

Male

Location

Fremont, California, USA

I am...

Engineer

My research field or area of interest innanotechnology

• Polymer modification (Bio-conjugation). • Surface modification of nanoparticles by grafting on approach technique. • Biocompatibility test, gene transfection (invitro/invivo), magnetofection. • 3D Electro-spinning, and Nanocomposite Fabrication (microgel, gold, magnetic and silica nanoparticles).

Interest in...

Polymer Synthesis and Processing: • Conjugation (Bio-conjugation) • 3D Electro-spinning, and Nanocomposite Fabrication (microgel, gold, magnetic and silica nanoparticles). Surface Modification and Biomaterials Development: • Surface-grafting and treatment or coating of Biomaterials for Tissue Engineering and Drug/Gene delivery. • Biocompatibility: Cell- Polymer matrix interactions, Cyto-toxicity, Biodegradation, . Publication List: 2008 1. Shanta Raj Bhattarai, et al. N-hexanoyl Chitosan Stabilized Magnetic Nanoparticles: Enhancement of Adenoviral-Mediated Gene Expression both In vitro and In vivo. Nanomedicine 2008, Vol. 4, P. 1462-154. 2. Shanta Raj Bhattarai, et al. Hydrophobically modified chitosan/gold nanoparticles for DNA delivery. Journal of Nanoparticle Research 2008, Vol. 10, P. 151-162. 3. Shanta Raj Bhattarai , et al. Novel Production Method and Invitro Cell Compatibility of Ti-6V-4Al Alloy for Tissue Engineering. Journal of Biomedical Materials Research A (2008, Vol. 86A, P. 289-299. 4. Shanta Raj Bhattarai, et al. Modified Chitosan Stabilized Magnetic Nanoparticles: Implication for Cellular Labeling and Magnetic Resonance Imaging (MRI). Journal of Nanobiotechnology, 2008, Vol. 6, P. 1-29. 5. Madhab Bajgai, Santosh Aryal, Shanta Raj Bhattarai, et al. Poly (ε- caprolactone) Grafted Dextran Biodegradable Electrospun Matrix: A Novel Scaffold for Tissue Engineering. Journal of Applied Polymer Science, 2008, Vol. 108, P. 1447-1454. 6. Shanta Raj Bhattarai, et al. Multifunctional Polycation Stabilized Gold Nanoparticles as a DNA Delivery Vector both In vitro and In vivo. (Under Preparation). 7. Shanta Raj Bhattarai, et al. Synthesis, Characterization and Biomedical Application of organ targetable Superparamagnetic Iron Oxide Nanoparticles. (Under Preparation). 2003 24. Narayan Bhattarai, Shanta Raj Bhattarai, et al. Novel Polymeric Micells of Amphiphilic Triblock Copolymer Poly (p-Dioxanone-co-L-Lactide)-block-Poly (ethylene glycol). Pharmaceutical research 2003, Vol. 20, P.2021-2027. 25. Narayan Bhattarai, Dong Il Cha, Shanta Raj Bhattarai, et al. Biodegradable Electrospun Mat; Novel Block Copolymer of Poly (p-dioxanone-co-L-Lactide)-b-Poly (ethylene glycol). Journal of Polymer Science Part B: Polymer Physics, 2003, Vol .41, P.1955-1964. 26. Narayan Bhattarai, Shanta Raj Bhattarai, et al. Aqueous Solution Properties of Amphiphilic Triblock Copolymer Poly (p-Dioxanone-co-L-Lactide)-block-Poly (ethylene glycol). European Polymer Journal. 2003, Vol. 39, P.1603-1608.

Publication list

2007 8. Shanta Raj Bhattarai, et al. Amphiphilic Triblock Copolymer Poly (p-Dioxanone-co-L-Lactide)-block- Poly (ethylene glycol), Enhancement of Gene Expression and Inhibition of Lung Metastasis by Aerosol Delivery. Gene Therapy, 2007, Vol. 14, 476-483. 9. Shanta Raj Bhattarai, et al. Laboratory Formulated Magnetic Nanoparticles for Enhancement of Viral Gene Expression in Suspension Cell Line (K562 cells). Journal of Virological Methods, 2007, Vol. 147, P. 213-218. 10. Shanta Raj Bhattarai, et al. N-acylated chitosan stabilized iron oxide nanoparticles as a novel nano-matrix and ceramic modification. Carbohydrate Polymers, 2007, Vol. 69, 3, P. 467-477. 11. Shanta Raj Bhattarai, et al. Carbon Nanotube-Hydroxyapatite Nanocomposite as a Nano Carrier for DNA. Material Science and Engineering C (2007, Vol. 28, P. 64-69. 12. Remant Bahadur K.C., Shanta Raj Bhattarai, et al. Novel Amphiphilic Triblock Copolymer Based on PPDO, PCL, and PEG: Synthesis, Characterization, and Aqueous Dispersion Colloids and Surfaces A: Physicochemical and Engineering Aspect, 2007, Vol.292, P. 69–78. 13. Remant Bahadur K.C., Shanta Raj Bhattarai, et al. Synthesis and characterization of amine functionalized amphiphilic block copolymer based on poly (ethylene glycol) and poly (caprolactone) Polymer International 2007, Vol. 56, P.518–524. 14. Santosh Aryal, Remant Bahadur K.C., Shanta Raj Bhattarai, et al. Organic/Inorganic matrix mediated synthesis of hydroxyapatite. Journal of Material Chemistry (2007, Article in press, Early View Available in online). 15. Remant Bahadur K.C., Kwan-Woo Kim, Shanta Raj Bhattarai, et al. Effect of Collector Temperature and Conductivity on the Conformation of Nylong-6 Electrospun Nanofibers. Fibers and Polymers (2007, Article in press). 16. Remant Bahadur K.C., Santosh Aryal, Shanta Raj Bhattarai, et al. Amphiphilic triblock Copolymer based on PPDO and PEG:Synthesis, Characterization and Aqueous dispersion. Journal of Applied Polymer Science 2007, Vol. 103, P. 2695-2702. 2006 17. Shanta Raj Bhattarai, et al. Hydrophilic nanofibrous structure of polylactide; fabrication and cell affinity. Journal of Biomedical Materials Research A. 2006, Vol.78, 2, P. 247- 57. 18. Shanta Raj Bhattarai, et al. Novel Block Copolymer (PDO/LLA-b-PEG-); Enhancement of DNA Uptake and Cell Transfection. Acta Biomaterialia, 2006, Vol. 2, P. 207-212. 19. Remant Bahadur K.C., Santosh Aryal, Shanta Raj Bhattarai, et al. Stabilization of gold nanoparticles by hydrophobically modified polycations. Journal of Biomaterial Science: Polymer Edition, 2006, Vol. 17, P. 579-589. 20. Santosh Aryal, Dharmaraj N, Shanta Raj Bhattarai, et al. Deposition of gold nanoparticles on electrospun MgTiO3 ceramic nanofibers. Journal of Nanosci Nanotechnology. 2006, Vol.6, 2, P.510-3. 21. Santosh Aryal, Shanta Raj Bhattarai, et al. Carbon nantubes assisted biomimetic synthesis of hydroxyapatite from simulated body fluide. Material Science and Engineering A, 2006, Vol.426, P. 202-207. 2005 22. Myung Seob Khil, Shanta Raj Bhattarai, et al. Novel fabricated matrix via electrospinning for tissue engineering. Journal of Biomedical Materials Research, 2005, Vol. 72B, P.117-124. 2004 23. Shanta Raj Bhattarai, et al. Novel Biodegradable Electrospun Membrane: Scaffold for Tissue Engineering. Biomaterials 2004, Vol. 25, 13, P. 2595-2602.

Researchgroup, Institute, University, School, Company name

Gene/Drug Delivery Group (Dr. David Oupicky Group)

Researchgroup, Institute, Company, University, School webpage

https://www.wayne.edu, Chori.org, lbnl.gov

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