Morgantown, WV


September 21

I am...


My research field or area of interest innanotechnology

Nanobioscience using P450 Proteins and Modified Oligonucleotides in Sensors

Interest in...

P450 Enzymes Protein-Protein Interactions DNA conformation Drug Design

Publication list

Vongsutilers, V., Daft, J.R., Shaughnessy, K.H., Gannett, P.M., Molecules “A General Synthesis of C8-Arylpurine Phosphoramidites”, 14:3339-3352 (2009). Yang, M., Kabulski, J.L., Wollenberg, L., Chen, X., Tracy, T.S., Gannett, P.M., Wu, N.N. “Electrocatalytic Drug Metabolism by Cytochrome P450 Enzyme Bonded to a Self-assembled Monolayer Modified Electrode”, (2009) Drug Metab. Disposition. 37:892-899. Wang, H., Cheatham, T.E., III, Gannett, P.M., Lewis, J.P. “Dynamics of A-B Transition of the DNA Double Helices”, Soft Matter, 5 685-690 (2009) Hummel, M.A., Gannett, P.M., Aguilar, J., and Tracy, T.S. “Substrate proton to heme distances in CYP2C9 allelic variants and alterations by the heterotropic activator, dapsone. Arch. Biochem. Biophys. 475 175-183 (2008) Gannett, P.M., Miller, L., Daft, J., Locuson, C., Tracy, T.S. “Synthesis of Deuterated Naproxens”, J. Labelled Compds. Pharmaceut. 50:1272-1275 (2007). Locuson, C.W., Gannett, P.M., Ayscue, R.R., Tracy, T.S., “Discovery of Heteroactivators of Cytochromes P450 Using Virtual Library Screening”, J. Med. Chem.. 50:1158-1165 (2007). Martirosyan, A., Leonard, S., Shi, X., Griffiths, B., Gannett, P.M., Strobl, J. ‘Dual Roles for Reactive Oxygen Species in MCF-7 Human Mammary Tumor Cell Differentiation and Cell Death Produced by an Experimental Agent, NSC3852', (2006) J. Pharmacol. Exp. Therapeutics 317:546-552. Locuson, C.W., Gannett, P.M., Tracy, T.S. “Heteroactivator Effects on the Coupling and Spin State Equilibrium of CYP2C9" (2006) Arch. Biochem. Biophys. 449:115-129. Mohler, D.L., Downs, J.R., Hurley-Predecki, A.L., Sallman, J.R., Gannett, P.M., Shi, X. ‘DNA Cleavage by the Photolysis of Cyclopentadienyl Metal Complexes: Mechanistic Studies and Sequence Selectivity of Strand Scission by CpW(CO)3CH3', (2005) J. Org. Chem. 70:9093-9102. Heavner, S. and Gannett, P.M. ‘Molecular Dynamics and Free Energy Calculations of the B and Z Forms of C8-Arylguanine Modified Oligonucleotides’, (2005) J. Biomolec. Struct. Dyn. 23:203-219. Darian, E. and Gannett, P.M. ‘Application of Molecular Dynamics to Spin-labeled Oligonucleotides’, (2005) J. Biomolecular Structure and Dynamics, 22:579-594.

Researchgroup, Institute, University, School, Company name

West Virginia University

Researchgroup, Institute, Company, University, School webpage

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