Gender

Male

Location

Chandigarh

Birthday:

May 14

I am...

Biologist

My research field or area of interest innanotechnology

Immunology

Interest in...

Infectious Diseases, Vaccine, Early diagnosis

Publication list

1. Gowthaman U, Agrewala JN. In silico metodes for predicting T cell epitopes: Dr. Jekyll or Mr. Hyde? (in press: Expert Opin Proteomics). 2. Gowthaman U, Agrewala JN. In silico tools for predicting peptides binding to HLA-class II molecules: more confusion than conclusion. J Proteome Res. 7:2008:154-63. 3. Mir MA, Agrewala JN. Signaling through CD80: an approach for treating lymphomas. Expert Opin Ther Targets. 12:2008:969-79. 4. Agrewala JN, Brown DM, Lepak NM, Duso D, Huston G, Swain SL. Unique ability of activated CD4+ T cells but not rested effectors to migrate to non-lymphoid sites in the absence of inflammation. J Biol Chem. 282:2007:6106-15. 5. Mir MA, Agrewala JN. Influence of CD80 and CD86 co-stimulation in the modulation of the activation of antigen presenting cells. Curr Immunol Rev. 3:2007:160-9. 6. Sharma S, Chopra K, Kulkarni SK, Agrewala JN. Resveratrol and curcumin suppress immune response through CD28/CTLA-4 and CD80 costimulatory pathway. Clin Exp Immunol. 147:2007:155-63. 7. Swain SL, Agrewala JN, Brown D, Gibbs DJ, Golech S, Huston G, Jones S, Kamperschroer C, Lee WH, McKinstry K, Roman E, Strutt T, Weng NP. CD4 memory: generation and multi-faceted roles for CD4 T Cells in protective immunity to influenza. Immunol Rev. 211:2006:8-22. 8. Singh V, Agrewala JN. Regulatory role of pro-Th1 and pro-Th2 cytokines in modulating the activity of Th1 and Th2 cells when B cell and macrophages are used as antigen presenting cells. BMC Immunol. 7:2006:17-26. 9. Ahmad N, Deeba F, Faisal SM, Khan A, Agrewala JN, Dwivedi V, Owais M. Role of fusogenic non-PC liposomes in elicitation of protective immune response against experimental murine salmonellosis. Biochimie. 88:2006:1391-1400. 10. Sharma S, Kulkarni SK, Agrewala JN, Chopra K. Curcumin attenuates thermal hyoperalgesia in a diabetic mouse model of neuropathic pain. Eur J Pharmacol. 536:2006:256-61. 11. Kaur N, Dhuna V, Kamboj SS, Agrewala JN, Singh J. A. Novel antiproliferative and antifungal lectin from Amaranthus viridis linn seeds. Protein Peptide Lett. 13:2006:897-905. 12. Kaur N, Singh J, Kamboj SS, Agrewala JN, Kaur M. Two novel lectins from Parkia biglandulosa and Parkia roxburghii: isolation, physicochemical characterization, mitogenicity and anti-proliferative activity. Protein Peptide Lett. 12:2005:589-95. 13. Bains JS, Dhuna V, Singh J, Kamboj SS, Nijjar KK, Agrewala JN. Novel lectins from rhizomes of two Acorus species with mitogenic activity and inhibitory potential towards murine cancer cell lines. Int Immunopharmacol. 9:2005:1470-8. 14. Singhbains J, Singh J, Kamboj SS, Nijjar KK, Agrewala JN, Kumar V, Kumar A, Saxena AK. Mitogenic and anti-proliferative activity of a lectin from the tubers of Voodoo lily (Sauromatum venosum). Biochim Biophys Acta. 1723:2005:163-74. 15. Sharma N, Agrewala JN. Potent role of the vaccines prepared from macrophages infected with live bacteria in protection against M. tuberculosis and S. typhimurium infections. J Infect Dis. 190:2004:107-14. 16. Suvas S, Vohra H, Agrewala JN. Modulation of the expression of M150 on macrophages by Th1/Th2 cytokines and co-stimulatory molecules CD40, B7-1, B7-2 and ICAM-1. Clin Exp Immunol. 134:2003:232-7. 17. Agrewala JN, Suvas S, Singh V, Vohra H. Delivery of antigen in allogeneic cells preferentially generates CD4+ Th1 cells. Clin Exp Immunol. 134:2003:13-22. 18. Suvas S, Singh, V, Sahdev, S, Vohra, H, Agrewala, JN. Distinct Role of CD80 and CD86 in the regulation of the activation of B cell and B cell Lymphoma. J Biol Chem. 277:2002:7766-75. 19. Swain, SL, Agrewala JN, Brown, D.M, Roman E. Regulation of memory CD4 T cells: generation, localization and persistence. Adv Exp Med Biol. 512:2002:113-20. 20. Raghavendra V, Singh V, Kulkarni SK, Agrewala JN. Melatonin enhances Th2 mediated immune responses: lack of sensitivity to reversal by naltrexone or benzodiazepine receptor antagonists. Mol Cell Biochem. 221:2001:57-62. 21. Raghavendra V, Singh V, Shaji AV, Vohra H, Kulkarni SK, Agrewala JN. Melatonin provides signal 3 to unprimed CD4+ T cells but failed to stimulate LPS primed B cell. Clin Exp Immunol. 124:2001:414-22. 22. Owais M, Masood AK, Agrewala JN, Bisht D, Gupta CM. Use of liposomes as an immunopotentiating delivery system: in perspective of vaccine development. Scand J Immunol. 54:2001:125-32. 23. Raghava GPS, Agrewala JN. A web-based method for computing endpoint titter and concentration of antibody/antigen. Biotech Software Internet Report. 2:2001:196-7. 24. Raghavendra V, Agrewala JN, Kulkarni SK. Melatonin reversal of lipolysaccharides-induced thermal and behavioral hyperalgesia in mice. Eur J Pharmacol. 395:2000:15-21. 25. Raghavendra V, Agrewala JN, Kulkarni SK. Role of centrally administered melatonin and inhibitors of COX and NOS in LPS-induced hyperthermia and adipsia. Prost Leuko Essen Fatty Acids. 60:1999:249-53. 26. Agrewala JN, Wilkinson RJ. Influence of HLA-DR on the phenotype of CD4+ T lymphocytes specific for an epitope of the 16-kD α-crystalline antigen of Mycobacterium tuberculosis. Eur J Immunol. 29:1999:1753-61. 27. Das G, Vohra H, Saha B, Agrewala JN, Mishra GC. Apoptosis of Th1-like cells in experimental tuberculosis. Clin Exp Immunol. 115:1999:324-8. 28. Das G, Vohra H, Saha B, Agrewala JN, Mishra GC. Leishmania donovani infection of a susceptible host results in apoptosis of Th1-like cells: rescue of anti-leishmanial CMI by providing Th1-specific bystander costimulation. Microbiol Immunol. 42:1998:795-801. 29. Agrewala JN, Wilkinson RJ. Differential regulation of Th1 and Th2 cells by p91-110 and p21-40 peptides of the 16-kD -crystalline antigen of Mycobacterium tuberculosis. Clin Exp Immunol. 114:1998:392-7. 30. Agrewala JN, Upma, Banyal HS. A 24,000g sediment of Plasmodium berghei induces IL-1 response in mice and exhibits protection against malaria infection. Parasitology (Hung). 31:1998:13-8. 31. Agrewala JN, Suvas S, Joshi A, Bhatnagar A, Vinay DS, Mishra GC. M150 modulates the costimulatory signals delivered by B cells to T cells and enhances their ability to help B cells. J Interferon Cytokines Res. 18:1998:297-304. 32. Agrewala JN, Suvas S, Verma RK, Mishra GC. Differential effect of anti-B7-1 and anti-M150 antibodies in restricting the delivery of costimulatory signals from B cells and macrophages. J Immunol. 160:1998:1067-77. 33. Shaji AV, Kulkarni SK, Agrewala JN. Regulation of secretion of IL-4 and IgG1-isotype by melatonin stimulated ovalbumin specific T cells. Clin Exp Immunol. 111:1998:181-5. 34. Agrewala JN, Kumar B, Vohra H. Potential role of B7-1 and CD28 molecules in immunosuppresion in leprosy. Clin Exp Immunol. 111:1998:56-63. 35. Agrewala JN, Deacock S, Jurcevic S, Wilkinson R. Peptide recognition by T cell clones of HLA-DRB1*1501/*901 heterozygous donor is promiscuous only between parental alleles. Hum Immunol. 55:1997:34-8. 36. Pitchappan RM, Agrewala JN, Dheenadayalan V, Ivanyi J. MHC-restriction in Tuberculosis. J Biosci. 22: 1997:47-56. 37. Jurcevic S, Travers P, Hills A, Agrewala JN, Moreno C, Ivanyi J. Distinct conformations of a peptide bound to HLA-DR1 or DRB5*0101 suggested by molecular modelling. Int Immunol. 8:1996:1807-14. 38. Agrewala JN, Owais M, Gupta CM, Mishra GC. Antigen incorporation into liposomes results in the enhancement of IL-4 and IgG1 secretion: evidence for preferential expansion of Th-2 cells. Cytokines Mol Ther. 2:1996:59-65. 39. Agrewala JN, Mishra GC. A 38kDa antigen of Mycobacterium tuberculosis predominantly induces the secretion of interleukin-2, interferon-gamma and IgG2a antibodies. Microbiol Immunol. 39:1995:801-8. 40. Raghava GPS, Agrewala JN. Method for determining the affinity of monoclonal antibody using non-competitive ELISA: a computer program. J. Immunoassays. 15:1994:115-28. 41. Vijayakrishnan L, Kumar V, Agrewala JN, Mishra GC, Rao KVS. Antigen-specific early primary humoral responses modulate Immunodominance of B cell epitopes. J Immunol. 153:1994:1613-25. 42. Agrewala JN, Vinay DS, Joshi A, Mishra GC. A 150-kDa molecule of murine macrophage membrane stimulates interleukin-2 and interferon- production and proliferation of ovalbumin-specific CD4+ T cells. Eur J Immunol. 24:1994:2092-7. 43. Ghei SK, Agrewala JN, Sengupta U, Sudhakar KS. Group specific component in Erythema Nodosum Leprosum. Ind J Lepr. 65:1993:323-5. 44. Agrewala JN, Raghava GPS, Mishra GC. Measurement and computation of murine interleukin-4 and interferon-g by exploiting the unique abilities of these lymphokines to induce the secretion of IgG1 and IgG2a. J Immunoassays. 14:1993:83-97. 45. Raghava GPS, Joshi, A and Agrewala JN. Calculation of antibody and antigen concentrations from ELISA data using a graphical method. J Immunol Methods. 153:1992:263-4. 46. Agrewala JN, Sinha S, Sengupta U. Caution when standardizing serum antibody competition assays. Trans Roy Soc Trop Med Hyg. 84:1990:137-8. 47. Agrewala JN, Sinha S, Ghei SK, Katoch K, Girdhar BK, Sengupta U. Demonstration of anti-dapsone antibody in leprosy patients. Int J Lepr. 57:1989:687-90. 48. Agrewala JN, Ghei SK, Sudhakar KS, Girdhar BK, Sengupta U. Human Leukocyte antigen and Erythema Nodosum Leprosum. Tissue Antigens. 33:1988:486-7. 49. Agrewala JN, Pant MC, Chaturvedi V, Upadhaya GL. Effect of feeding decoction of Carum copticum on LDL, VLDL, HDL, and SCBR in albino rabbits. Ind Drugs. 23:1986:1-6. 50. Agrewala JN, Pant MC. Effect of feeding Carum copticum seeds on serum lipids, high-density lipoproteins and serum cholesterol binding reserve in albino rabbits. Ind J Med Res. 83:1986: 93-5.

Researchgroup, Institute, University, School, Company name

Institute of Microbial Technology

Researchgroup, Institute, Company, University, School webpage

https://www.imtech.res.in

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