Reya Rene Philip and Dr. D Sankari

Department of Biotechnology, College of Science and Humanities,
SRM Institute of Science and Technology


Biocompatibility and acceptability are the two biggest obstacles for any drug delivery method because synthetic materials interact very differently with human body cells than biological ones do. Significant difficulties arise when using large-scale materials for drug delivery, including in vivo instability, poor bioavailability and solubility, poor body absorption, problems with target-specific delivery, issues with tonic efficacy, and possibly harmful drug effects.
Nanotechnology has been found to link the barrier between the physical and biological sciences by utilizing nanostructures and nanophases in various science fields, particularly in nanomedicine and nano-based drug delivery systems, where such particles are of major interest. In the developing area of nanomedicine, medical biology, disease prevention, and treatment are all approached using the knowledge and methods of nanoscience. It promotes using nano-dimensional materials for nanorobots, nanosensors for delivery, diagnostics, sensory functions, and actuate materials in living cells.
Nanodrug systems have been utilized to enhance the effectiveness, safety, physicochemical properties, and pharmacokinetic/pharmacodynamic profile of pharmaceutical substances. Particularly, functionalized nano-drug systems can provide a prolonged half-life of injected drugs and targeted delivery to particular tissues, as well as improved bioavailability of drugs taken orally. As a result, nano-drug delivery systems may reduce the frequency of administration while maximizing pharmacological effects and minimizing systemic side effects, potentially improving therapeutic compliance and clinical outcomes. The application of nanotechnology to medicine, and more particularly to the delivery of drugs, is expected to multiply. This review demonstrates how valuable nano drugs are for various treatments.

Drug delivery, Bioavailability, Nanotechnology, Treatments, Nanoparticles

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