A postdoc position is available in the Computational Molecular Biophysics Group at Georg-August-University Göttingen. The University of Göttingen is a research university of international renown and the Göttingen research campus is among world-leading locations for molecular biophysics. Our group applies computer simulations to study the structure, function, and dynamics of biological Macromolecules. Payment will be according to TV-L E13 (west). The employment is limited to two years with possibilities for an extension.

Project

Small-angle and wide-angle X-ray scattering (SAXS/WAXS) are experimental techniques which can provide structural information about biomolecules (proteins, DNA, RNA) in solution and, thus, under physiological conditions. In addition, such methods even yield time-resolved insight into conformation transitions of biomolecules, and could therefore in principle observe these intriguing molecular machines "in action".

Unfortunately, the interpretation of (time-resolved) SAXS/WAXS patterns is difficult and therefore restricts a wider application of the method. We will employ molecular dynamics simulations, carried out on high-performance computing facilities, with the aim to derive an atomistic interpretation of solution scattering data, with a strong focus on recent developments towards wide-angle signals. The project will be carried out in close collaboration to experimental groups in Göttingen, Gothenburg and Grenoble, and can include a research stay in Stockholm or Uppsala. The detailed direction of the project will be decided together with the applicant.

Applicant

We are looking for a highly motivated and team-oriented fellow who is interested to work in a young research group. The applicant should have a PhD in physics, chemistry, bioinformatics, or a related subject. The applicant should have a strong background in molecular dynamics simulations (preferably methods development) or solution scattering experiments, as well as experience in programming and Linux/Unix-like environments. Most important is a strong interest in computational structural biology and the ability to collaborate with experimentalists.

Please send your full application until January 4th 2015 to Dr. Jochen Hub (jhub@gwdg.de). The application should include a brief statement of research interests, a scientific CV and the names of 3 references.

The University of Göttingen is an equal opportunities employer and places particular emphasis on fostering career opportunities for women. Qualified women are therefore strongly encouraged to apply as they are underrepresented in this field. Disabled persons with equivalent aptitude will be favored.

We are looking forward to hear from you.