PLEASE ANY ANYONE HELP ME FOR THIS QUERY

PLEASE ANY ANYONE HELP ME FOR THIS QUERYIn FESEM plant synthesized Titanium nanoparticles were aggregated into clumps. we didnt tried ultra sound sonication to separate them. i want to know, What kind of distribution or level of packing would that yield? It seems to me that if the packing problem cannot be well solved, then this method is highly limited in terms of applications.
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