PhD thesis position: Elaboration of novel antibacterial implant surfaces based on the attachment of biomolecules on a bioinspired functional plasma thin film

The Public Research Centre - Gabriel Lippmann, a public establishment for applied scientific research and technology transfer, has an opening for a fixed-term position for its "Science and Analysis of Materials" department (SAM) that focuses in the following fields: nanotechnologies and nanomaterials, smart functional materials, surface treatment and thin films, development of nano-analytical instrumentation and advanced characterization of materials for:

 

 

A PhD thesis position  (m/f)

(ref: SAM-20140805-PHDMETABIO)

 

 

Topic: Elaboration of novel antibacterial implant surfaces based on the attachment of biomolecules on a bioinspired functional plasma thin film.

 

Description of the position:

The PhD position is opened in the framework of the European METABIO project in partnership with the University of Liège (Ulg, Belgium), a start-up company (Belgium) and two industrial companies in Luxembourg and in Italy.

The research project aims at developing a novel surface treatment conferring antibacterial and Osseo integration properties to dental implant surfaces. The PhD work will contribute to a deeper understanding of a plasma bio-inspired film growth mechanism and of the chemical kinetics between biomolecules and plasma coated surfaces. In this study, biomolecules will include peptides, proteins or enzymes with bactericidal and antibiofilm properties.


The PhD work will be organized around the different following tasks:

- the PhD student will participate to the set-up of a plasma process able to deposit a functional bioinspired

thin film on 3D dental implants.

- she/he will investigate the influence of the different process parameters (i.e, electrical discharge

power and mode, precursor flow…) on the deposited layer properties. For that, she/he will carry out

the layer characterization by combining different analytical techniques such as FT-IR, XPS, UV, SEM

and AFM analyses.

- she/he will also be in charge of the biomolecule immobilization on the plasma deposited film. In

particular, immobilization conditions, such as pH, ionic strength or temperature of the solution, will

be optimised to ensure a fast and efficient biomolecule attachment.

With strong analytical and synthetic skills, the PhD student will have to establish clear correlations between layers chemistry/morphology, antibacterial-Osseo integration properties and cellular response for dental applications.

At the end of the project, it is planned to transfer the technology for the treatment of 3D dental implants and to validate the concept through in-vitro tests.

Profile:

-A master degree in sciences, preferably in chemistry, biomaterials or surface sciences

-The candidate has to be motivated, to be structured and self-responsible.

-The applicant must show his/her willingness to develop good skills in the fields of experimental

investigations and characterization techniques.

-Good spoken and written English is mandatory, knowledge of French would be an asset

Candidates interested in the above position can apply online. The application file should include a CV, a motivation letter, the names of two or three referees, the last diploma and marks obtained at the university.

 

For any question regarding our job offers or the application process, please contact our recruitment team at recrutement@lippmann.lu


Click here to apply from our website

Views: 56

Tags: TINC-Job, monitor

Comment

You need to be a member of The International NanoScience Community to add comments!

Join The International NanoScience Community

Next partner events of TINC

We are Media Partner of:

Welcome - about us

Welcome! Nanopaprika was cooked up by Hungarian chemistry PhD student in 2007. The main idea was to create something more personal than the other nano networks already on the Internet. Community is open to everyone from post-doctorial researchers and professors to students everywhere.

There is only one important assumption: you have to be interested in nano!

Nanopaprika is always looking for new partners, if you have any idea, contact me at editor@nanopaprika.eu

Dr. András Paszternák, founder of Nanopaprika

Publications by A. Paszternák:

The potential use of cellophane test strips for the quick determination of food colours

pH and CO2 Sensing by Curcumin-Coloured Cellophane Test Strip

Polymeric Honeycombs Decorated by Nickel Nanoparticles

Directed Deposition of Nickel Nanoparticles Using Self-Assembled Organic Template,

Organometallic deposition of ultrasmooth nanoscale Ni film,

Zigzag-shaped nickel nanowires via organometallic template-free route

Surface analytical characterization of passive iron surface modified by alkyl-phosphonic acid layers

Atomic Force Microscopy Studies of Alkyl-Phosphonate SAMs on Mica

Amorphous iron formation due to low energy heavy ion implantation in evaporated 57Fe thin films

Surface modification of passive iron by alkylphosphonic acid layers

Formation and structure of alkylphosphonic acid layers on passive iron

Structure of the nonionic surfactant triethoxy monooctylether C8E3 adsorbed at the free water surface, as seen from surface tension measurements and Monte Carlo simulations

Photos

  • Add Photos
  • View All