The Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. is located in Dortmund and Berlin. Besides scientific activities in the development of new or improved measuring methods and analytical separation techniques as well as spectroscopy and spectrometric equipment in modern analysis, research is undertaken in the areas of spectroscopic methods and analytical contributions to solving problems in the fields of materials and life sciences.

We invite applications for a

PhD student position (m/f)

in signaling proteomics for the time-resolved mass spectrometry-based characterization of cellular signaling events that regulate human platelets and their involvement in thrombosis and hemostasis.

As a member of the Signaling Proteomics research team you will be responsible for:

• Developing and improving methods for the mass spectrometry-based quantification of phosphorylation and further post-translational modifications (PTMs)
• Utilizing these methods for the quantification of signaling events involved in the physiological/ pathophysiological activation of platelets – in close collaboration with clinical partners
• Presenting and publishing data
• Assisting in the supervision of a state-of-the-art nano-LC-MS/MS system

Your profile:

• Masters, Diploma or equivalent degree in biochemistry/ chemistry/ pharmacy that allows direct admission for doctoral studies in Germany
• Strong background and interest in protein chemistry, analytical (bio-)chemistry and mass spectrometry, experimental research experience
• Scientific creativity and passion for solving complex biological questions
• Willingness to learn and develop novel methods, to demonstrate initiative and responsibility, and to work in an interdisciplinary team
• Good working knowledge of English, good computer skills

We offer:

• Excellent training and support to develop and contribute one’s personal skills and pursuit state-of-the-art research projects
• A good working atmosphere in a very dynamic, international and professional team
• Extensive state-of-the-art equipment and infrastructure for MS-based quantitative proteomics
• Hands on experience in LC-MS techniques
• The opportunity to present your data on international conferences and participate in workshops

Non-residents who apply for this job will receive help from the institute to find accommodation. Applications from disabled applicants are welcome. ISAS supports the principle of equal opportunity between men and women, and is therefore interested in applications from women.

The salary will be according to the German TV-L (E13). This position is a part-time work (60%) and is offered for three years. The position is available immediately.

Closing date for application is February 10th 2014. Complete applications with curriculum vitae, 2 references and copies of certificates should be submitted (quoting the reference number 2/2014 in the subject header) as a single pdf.document to personal@isas.de.

Informal inquiries are welcome and can be submitted to the human resources department (personal@isas.de).
For further information on the institute please see: http://www.isas.de