New Atomic Force Microscopy Seminar!
Agilent Technologies invites you to attend new scientific e-Seminars in October. These exclusive one-hour live events provide a great opportunity to learn about the latest AFM instrumentation and techniques for biological applications and advanced methods for AFM imaging modes There will also be a Q&A session in which all online attendees can query the presenters directly.
Register now for these informative seminars!
"Lively Complements"
Date: October 21 @ 15:00. CET
Price: Free!
Topic 1: Combining Light Microscopy with Scanning Probe Microscopy for Biological Applications
Gerald Kada, Ph.D. (Agilent Technologies, Linz, Austria)
The combination of fluorescence microscopy and atomic force microscopy has great potential for single-molecule-detection applications, overcoming the limitations inherent to each technique and revealing more detailed information about structure and localization of membrane and cytoskeleton features. AFM itself has evolved from a mere nanoscale visualization tool into a complex mechanical and biological sensing tool via use of modified tips for biological recognition imaging.
Simultaneous topography and recognition imaging becomes even more powerful when combined with fluorescence microscopy in a novel platform; examples on various cell systems will be shown.
Topic 2: Accurate Localization of Cell Membrane Receptors Using Combined Fluorescence and Recognition Imaging
Memed Duman, Ph.D. (Institute for Biophysics, University of Linz, Austria)
A new platform of combined fluorescence and simultaneous topography and recognition imaging (TREC) for improved localization of cell receptors will be presented. While expression level, distribution, and localization of YFP-labeled CD1d molecules on α-galactosylceramide (αGalCer)-loaded THP1 cells were detected with fluorescence microscopy, nanoscale distribution of binding sites was investigated with molecular recognition imaging via a chemically modified AFM tip. Using TREC on an inverted light microscope, recognition sites of cell receptors were detected in recognition images with domain sizes ranging from ~25 to ~160 nm, with the smaller domains corresponding to single CD1d molecules.
"Beyond Tapping Mode"
Date: October 27 @ 15:00 CET
Topic: Advanced Imaging Modes Based on the Oscillation of an AFM Cantilever
Song Xu, Ph.D. (Agilent Technologies)
Many advanced imaging modes based on cantilever oscillating technology have been developed to map the physical and chemical properties of materials.
Such imaging modes include phase imaging, magnetic force microscopy, electrostatic force microscopy, Kelvin force microscopy, and topography recognition (TREC), among others. We will discuss the basic physics behind these advanced AC imaging modes, the mathematics of the feedback mechanisms utilized, and several example applications drawn from a variety of research fields.
Join us for these exciting live events!
Agilent e-Seminars feature a user-friendly, web-based conferencing system that allows you and your colleagues to take part in real-time, interactive presentations on subjects that are pertinent to your work.
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