Enzymes and Molecular Machines Can Be Selected from Random Copolymers

Such functional copolymers as the proteins are called "mechanomers" here (distinguishing naturally-occurring mechanomers as "biopolymers" where convenient); the science of mechanomers is called "mechanomerics"; and applied mechanomerics is called "mechanomeric engineering", including "mechanomeric medicine".

Mechanomeric engineering requires some technique for developing mechanomers to perform desired functions, such as enzymes and molecular machines.

And just as proteins are developed in nature by variation of amino acid order—and therefore of protein conformation (coiled structure), and therefore of shape, mechanical properties and surface structure, and therefore of function—followed by selection, so too artificial mechanomers can be developed by selecting those performing desired functions from among random mechanomers, mechanomers with random  monomer orders, conformations, shapes, mechanical properties, surface structures and functions, in what is called here "mechanomeric selection".

Evolution's scale, in numbers of mechanomers/biopolymers and selections and across time, keeps it from being proof that mechanomeric selection is a practicable technology.

However, the development of each individual's antibody complement in childhood, and still more such development in the even smaller and faster system of the duck embryo in the egg, and the function of those antibodies, and most of all the medical exploitation of such development and function in vaccination and the medical and industrial development and use of antisera and monoclonal antibodies, all furnish so many everyday small-scale proofs that proteins performing such more or less simple complexings or molecularrecognitions as antibodies can be developed by random synthesis followed by selection.

Enzyme function furnishing so many more examples of such complexings, enzymescan therefore be developed likewise.

Proteins performing any equally simple functions or small combinations thereof likewise.

Biopolymers of the other important class of such, the nucleic acids, likewise, within the limitations imposed by their smaller numbers of kind of monomers (and smaller variations in structure between those).

And mechanomers of other classes likewise . . . .


Views: 174


You need to be a member of The International NanoScience Community to add comments!

Join The International NanoScience Community

Welcome - about us

Welcome! Nanopaprika was cooked up by Hungarian chemistry PhD student in 2007. The main idea was to create something more personal than the other nano networks already on the Internet. Community is open to everyone from post-doctorial researchers and professors to students everywhere.

There is only one important assumption: you have to be interested in nano!

Nanopaprika is always looking for new partners, if you have any idea, contact me at editor@nanopaprika.eu

Dr. András Paszternák, founder of Nanopaprika

Partner network:

Next partner events of TINC

We are Media Partner of:



© 2018   Created by András Paszternák, PhD (founder).   Powered by

Badges  |  Report an Issue  |  Terms of Service