PhD in Stem Cell Biology - UCL, UK

A 3 year PhD studentship is available at the Centre for Regenerative Medicine and Nanotechnology at University College London (UCL). Founded in 1826, UCL, placed fourth in the QS World University Rankings 2013/14, and is one of the world’s leading universities focused on research excellence and teaching.



The studentship, based in the laboratory of Dr. Ashleigh Boyd, is focused on stem cell biology. Stem cell biology research has the potential to revolutionize the clinical armamentarium for debilitating diseases caused by ageing, organ failure and cancer. Dr. Boyd’s laboratory is studying the potential applicability of pluripotent stem cells to enhance the treatment of Type 1 diabetes mellitus (hereafter diabetes). We are focusing on one type of pluripotent stem cell called an induced pluripotent stem cell (iPSC). iPSCs are adult cells (e.g. skin cells) that are ‘reprogrammed’ back to a stem cell state via the introduction of transcription factors responsible for the maintenance of stem cell characteristics.

Studentship Description
As iPSCs can in principle produce all tissues in the body, they have the ability to impact treatment of diabetes in terms of providing tissues for transplantation to restore normal insulin production. In addition, the ability to generate iPSCs from diabetic patients offers the unprecedented opportunity to dissect and understand the development and pathogenesis of diabetes and, in so doing, to identify potential therapeutic targets. The focus of this project is to use iPSCs derived from diabetic patients (and other related systems) to model the immunological defects underlying the disease and use this information to devise nanotechnology based methods to overcome these effects. The student will gain a firm grounding in cellular and molecular biology as well as exposure to nanotechnology during their training.
Person Specification

The studentship, to commence in January 2015, will cover a tax-free stipend for living expenses (to start at £15,160 per year), tuition fees (for UK/EU students only) and bench consumables for experiments. The successful candidate will have obtained a 1st class or 2 (i) honours degree from a UK University or equivalent (for EU countries). In short-listing candidates, preference will be given to students who have experience in pluripotent stem cell biology techniques (e.g IPSC culture) and post-graduate/other research experience (e.g as a Research Assistant).

Eligibility

To make an application please send a CV and the contact details, including email addresses for two referees, to: a.boyd@ucl.ac.uk.  Please include a covering letter indicating why you believe you are suitable for the studentship, your long-term research and professional goals, and any particular expertise you have that you feel may be applicable in this work.



This studentship is open to UK and EU Nationals only.

Contact name
Dr Ashleigh Boyd
Contact details
UCL Taking Action for Equality
Closing Date
16 Nov 2014
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