Open 12 PhD and 2 postdoc positions in all fields related to lipid research. SNAL project http://itn-snal.net/ combines computer simulations, chemical synthesis, clinical and industrial expertise, physical and biological experiments to design and test completely new synthetic nano-objects that mimic the essential properties of membrane interacting biopolymers. The full cycle of the design process, from theoretical models to synthesis and experimental and clinical validation, is of particular importance for training of Early Stage Researchers (ESRs) and their future career development.

Description

The aim of this project is to understand the interactions of lipid membranes with nano-objects including functional biomimetic polymers, polymeric micelles, carbon nanotubes and polymer therapeutic complexes/conjugates to enable the intelligent design of novel materials with improved bilayer modifying properties. The project combines computer simulations, chemical synthesis, clinical and industrial expertise, physical and biological experiments. Complementarity of partner skills provides a logical basis for a collective training programme. The full cycle of the design process, from theoretical models to synthesis and experimental and clinical validation, is of particular importance for training of ESRs and their future career development. OPEN PHD PROJECTS ESR1-T: Equilibrium structures of lipid membranes and nano-objects ESR2-T: Molecular models of self-assembly of biomimetic polymers in lipid bilayers ESR3-D: Monte Carlo simulations of lipid membranes and their interactions with copolymer chains ESR4-D: Molecular dynamics simulations of phosphor-lipid bilayers and their interactions with nano-objects ESR5-L: Synthesis and characterization of functional biomimetic polymers for intracellular delivery ESR6-L: Atomistic and coarse-grained simulations of the interactions of nano-objects and biosurfactants with lipid bilayers ESR7-S: Optical microscopy and microrheology of giant unilamellar vesicles interacting with nano-objects ESR8-S: Dynamics of nanoscale structural changes occuring in small unilamellar vesicles ESR9-M: Investigation of interaction of membrane-lytic molecules with lipid monolayer ESR10-C: Bioengineering of membrane associating polymers and polymer-protein complexes ESR11-F: Toxicity of nano-objects on human cells models ESR12-F: Delivery of molecular payloads through primary human cell membrane OPEN POSTDOC PROJECTS ER1-U: Delivery of skin bioactives to assess the impact of membrane lytic biopolymers ER2-B: Investigation of membrane permeating materials in biostabilisation SALARY AND BENEFITS Researchers employed by SNAL will receive salary and benefits at the rates stipulated by the European Commission for Marie Curie researchers. The Researchers will be employed via full employment contracts with the respective institutions, carrying social benefits such as pension and social security, but also subject to normal taxes. Their income will consist of: · a living allowance and mobility allowance · yearly travel allowance · a career development allowance

Benefits

Researchers employed by SNAL will receive salary and benefits at the rates stipulated by the European Commission for Marie Curie researchers. The Researchers will be employed via full employment contracts with the respective institutions, carrying social benefits such as pension and social security, but also subject to normal taxes. Their income will consist of: · a living allowance and mobility allowance · yearly travel allowance · a career development allowance

Additional Job Details

APPLY The applications for all positions and requests are done through the contact form at http://itn-snal.net/positions/