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Marcus Maher
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Marcus Maher's Page

Profile Information

I am...
Chemist, Biologist, Teacher, User of nanotechnology products
My research field or area of interest innanotechnology
I have previously worked with: Simulation modelling of nanoparticle toxicity, Quantitative structure activity relationships (QSARs), Nanoparticle phisico-chemical characterisation, Viability and several biochemical marker assays, Acellular assay design, DNA expression, Protein purification and charaterisation, Enzyme kinetics and thermodynamics, Human cell culture and Aseptic technique.
Interest in...
Nanotechnology, Simulation Modelling, Toxicology, Analysis of how nanoparticle physico-chemical properties impact cellular systems, role of uptake mechanics in mediation of toxicity, prediction of nano-txicity based on particle reactivity (with a non-cellular assay system),
Publication list
Maher, M.A., Naha, P.C., Mukerjee, S.P. and Byrne, H.J. 2014. Numerical simulations of in vitro nanoparticle toxicity – the case of Poly (amido amine) dendrimers. Toxicol. In Vitro, 28(8), 1449-1460.

Maher, M.A., Khalid, H. and Byrne, H.J. 2016. Acellular reactivity of polymeric dendrimer nanoparticles as an indicator of oxidative stress in vitro. Anal. Bioanal. Chem., 408(3), 695–703.

Maher, M.A. and Byrne, H.J. 2016 – B. Modification of the in vitro uptake mechanism and antioxidant levels in HaCaT cells and resultant changes to toxicity and oxidative stress of G4 and G6 Poly (amido amine) dendrimer nanoparticles. Anal. Bioanal. Chem., 408(19), 5295-5307.

Sharkey, M.A., Maher, M.A., Guyonvarch, A. and Engel, P.C. 2011. Kinetic characterisation of recombinant Corynebacterium glutamicum NAD+-dependent LDH over-expressed in E. coli and its rescue of an lldD− phenotype in C. glutamicum: the issue of reversibility re-examined. Archives of Microbiology, 193(10), 731-740.

Farhane, Z., Bonnier, F., Maher, M.A., Bryant, J., Casey, A. and Byrne, H.J. 2016. Differentiating responses of lung cancer cell lines to Doxorubicin exposure: in vitro Raman micro spectroscopy, oxidative stress and bcl-2 protein expression. J. Biophotonics, DOI: 10.1002/jbio.201600019.
Researchgroup, Institute, University, School, Company name
FOCAS Research Institute, Dublin Institute of Technology.
Researchgroup, Institute, Company, University, School webpage
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